Second HPC Applications in Precision Medicine Workshop

ISC18

Frankfurt, Germany

June 28

9:00 AM – 6:00 PM

Location

Marriott Hotel  - Hamburger Allee

Second Floor - Alabaster 1

UPDATED AGENDA

Morning Session

Foundations for Precision Medicine Applications in High Performance Computing

9:00 AM Vision, Opportunities and Challenges

• Scott Hammond – University of California San Francisco (USA)
• “Practical challenges for biomedical modeling using HPC” – David Wright,  Robin Richardson and Peter Coveney  - University College of London (UK)

10:15 AM        Data Foundations for HPC and Precision Medicine

• Nicolas Hengartner – Group Leader Los Alamos National Laboratory (USA)

11:00 AM – 11:30 AM Coffee Break

11:30 AM – 12:30 PM Data Foundations for HPC and Precision Medicine (continued)

• “Lyra - containerized microservices for browsing shared biomedical data” - Michael Huttner, Rainer Spang, Claudio Lottaz, Stefan Hansch and Christian Kohler – University of Regensburg (Germany)
• “Real world medical data – Filling the gaps: Fusing health register with survey data to create a rich temporal dataset” - Ghaleb Abdulla, Hang Deng, Braden Soper, Lawrence Livermore National Laboratory (USA),  Jan Nygard and Mari Nygard, Cancer Registry of Norway (Norway)

12:30 PM Discussion

12:45PM – 2 PM Lunch Break

Afternoon Session

HPC Application Areas in Precision Medicine

2:00 PM Keynote AI in Precision Medicine

• Rick Stevens - Associate Laboratory Director for Computing, Environment and Life Sciences – Argonne National Laboratory (USA)

2:45 PM Discussion

3:00 Mini-Session - HPC and Drug Discovery

• Accurate and Precise Binding Affinity Calculations for Drug Development and Precision Medicine – Shunzhou Wan, Jumana Dakka, Kristof Farkas-Pall, Vivek Balasubramanian, Matteo Turilli, David Wright, Stefan Zasada, Shantenu Jha and Peter Coveney, University College of London (UK)

• ATOM – Accelerating Therapeutics for Opportunities in Medicine –  Dr. Deirdre Olynick – University of California San Francisco (USA)

3:45 PM Discussion

4:00-4:30 Coffee Break

4:30 Mini-Session - HPC and Cancer

• Recap of ISC18 Session on HPC in Medicine – Computational Approaches to Cancer – Prof. Dr. Tilo Wettig, University of Regensburg (Germany)
• An HPC Application to Population-Level Cancer Screening Data  - Braden Soper, Rui Meng, Ghaleb Abdulla, Lawrence Livermore National Laboratory (USA), Jan Nygard and Mari Nygard, Cancer Registry of Norway (Norway)
• Distinguishing between Normal and Cancer Cells Using Autoencoder Node Saliency - Ya Ju Fan, Jonathan Allen, Sam Ade Jacobs and Brian Van Essen – Lawrence Livermore National Laboratory (USA)

5:30 Updates, Discussion and Moving Forward

• US National Cancer Institute and Department of Energy Collaboration Updates
• Predictive model Interoperability, Portability and Access
• Guided discussion on key topics

6:00 Workshop Concludes