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  1. caNanoLab: data sharing to expedite the use of nanotechnology in biomedicine

    13 Dec 2013 | Publications | Contributor(s): Sharon Gaheen, George W Hinkal, Stephanie A Morris, Michal Lijowski, Mervi Heiskanen, Juli Klemm

    The use of nanotechnology in biomedicine involves the engineering of nanomaterials to act as therapeutic carriers, targeting agents and diagnostic imaging devices. The application of nanotechnology in cancer aims to transform early detection, targeted therapeutics and cancer prevention and...

  2. Genome-wide transcriptional sequencing identifies novel mutations in metabolic genes in human hepatocellular carcinoma (HCC)

    02 Feb 2014 | Publications

    Hepatocellular carcinoma (HCC) is the fifth most common cancer and the third most common cause of cancer mortality in the world. Although the association of HCC with chronic liver disease is well established, the exact etiology of HCC remains undefined. Here, we report the results of...

  3. 2014 QIN Abstract Book

    18 Apr 2014 | Publications | Contributor(s): Larry Clark

    The QIN Face-to-Face Meeting Presentations Posters and Abstracts.

  4. OmicCircos: A Simple-to-Use R Package for the Circular Visualization of Multidimensional Omics Data

    28 Apr 2014 | Publications | Contributor(s): Hu Y, Chunhua Yan, Hsu CH, Chen QR, Niu K, Komatsoulis GA, Meerzaman D.

    OmicCircos is an R software package used to generate high-quality circular plots for visualizing genomic variations, including mutation patterns, copy number variations (CNVs), expression patterns, and methylation patterns. Such variations can be displayed as scatterplot, line, or text-label...

  5. Three transplantable mouse mammary tumor models of human breast cancer were used to assess the effects of fixation on morphology and the preservation of 4 breast antigens (ER, PR, Ki67, Her2).

    04 Jun 2014 | Publications | Contributor(s): Neil Hubbard

    Quantitative Image Analysis (QIA) of digitized whole slide images for morphometric parameters and immunohistochemistry of breast cancer antigens was used to evaluate the technical reproducibility, biological variability, and intratumoral heterogeneity in three transplantable mouse mammary tumor...

  6. Economic Costs of Cancer Health Disparities Report

    26 Jul 2014 | Publications | Contributor(s): CRCHD

    Identify methodological and philosophical issues involved in filling the gap in our understanding of the economic costs of cancer health disparities from these proceedings and recommendations

  7. National Cancer Institute Catalyzing Trans-disciplinary Regional Partnerships to Eliminate Cancer Health Disparities

    26 Jul 2014 | Publications | Contributor(s): CRCHD

    Provides highlights of the opinion health disparities research and groundbreaking endeavors from Summit ‘07, including insights from media experts on how to effectively interact with minority media outlets

  8. Working Group Invitation: Image Quality in Whole Slide Imaging and Pathologist Performance

    06 Aug 2014 | Publications | Contributor(s): Brandon D. Gallas

  9. Lessons from a red squirrel, mentors, and the pathway to success.

    12 Sep 2014 | Publications | Contributor(s): Reinhart A.F. Reithmeier

    In this article, Dr. Reithmeier reviews his personal career path starting with how a red squirrel got him interested in research, and the vital role that mentors played in his pathway to success; a pathway that taught him many lessons that he would like to share with particularly graduate...

  10. Integrated analysis of breast cancer cell lines reveals unique signaling pathways

    16 Sep 2014 | Publications | Contributor(s): Laura M Heiser, Nicholas J Wang, Carolyn L Talcott, Keith R Laderoute, Merrill Knapp, Yinghui Guan, Zhi Hu, Safiyyah Ziyad, Barbara L Weber, Sylvie Laquerre, Jeffrey R Jackson, Richard F Wooster, Wen Lin Kuo, Joe W Gray, Paul T Spellman

    AbstractBackgroundCancer is a heterogeneous disease resulting from the accumulation of genetic defects that negatively impact control of cell division, motility, adhesion and apoptosis. Deregulation in signaling along the EgfR-MAPK pathway is common in breast cancer, though the manner in which...