Day 1, Wednesday, May 31 Session Chair: Obi Griffith Resources 1 PI Name(s) Title Institute 8:30 a.m. Talk Obi Griffith Development of Informatics Resources for Interpretation of Clinically Actionable Variants in Cancer Washington University in St. Louis 8:50 a.m. Talk Terry Meehan The PDX Integrator – Re-Purposing KOMP2 Informatics to Widely Disseminate Data from Patient Derived Xenografts and Electronic Access to Mouse Tumor Data European Molecular Biology Laboratory, and Jackson Laboratory 9:10 a.m. Talk John Weinstein, Bradley Broom Next-Generation Clustered Heat Maps for Fluent, Interactive Exploration of Omic Data University of Texas MD Anderson Cancer Center 9:30 a.m. Talk Levi Waldron Cancer Genomics: Integrative and Scalable Solutions in R / Bioconductor Roswell Park Cancer Institute 9:50 a.m. Talk Rachel Karchin Informatics Tools for High-Throughput Analysis of Cancer Mutations Johns Hopkins University 10:10 a.m. Talk Michael J Becich Advanced Development of TIES-Enhancing Access to Tissue for Cancer Research University of Pittsburgh 10:30 a.m. Break Session Chair: Joel Saltz Imaging 1 PI Name(s) Title Institute 10:45 a.m. Talk Xiaodong Wu Developing Enabling PET-CT Image Analysis Tools for Predicting Response in Radiation Cancer Therapy University of Iowa 11:05 a.m. Talk Lauren Jean O’Donnell Open Source Diffusion MRI Technology for Brain Cancer Research Harvard Medical School 11:25 a.m. Talk Christos Davatzikos Cancer Imaging Phenomics Software Suite: Application to Brain and Breast Cancer University of Pennsylvania 11:45 a.m. Talk John Quackenbush Quantitative Radiomics System Decoding the Tumor Phenotype Dana-Farber Cancer Institute 12:05 p.m. Lunch Get together of the TOW WG New Groups Lightning Talks Vincent Carey, Nathalie Pochet, and Raja Mazumder 1:15 p.m. Flash Talk Vincent Carey Accelerating Cancer Genomics with Cloud Scale Bioconductor Brigham & Women’s Hospital, Channing Division of Network Medicine 1:20 p.m. Flash Talk Nathalie Pochet Integrative genomic framework for dissecting regulatory mechanisms underlying hepatocellular carcinoma Brigham & Women’s Hospital, Neurology 1:25 p.m. Flash Talk Raja Mazumder Integration of comprehensive cancer mutation and expression-associated data for biomarker evaluation and discovery George Washington School of Medicine & Health Sciences Each new group gets 4 minutes to talk and show one slide, 3 groups total Session Chair : Guergana Savova Clinical 1 PI Name(s) Title Institute 1:30 p.m. Talk Hua Xu, Ping Yang Advancing Cancer Pharmacoepidemiology Research Through EHRs and Informatics The University of Texas Health Science Center at Houston, and Vanderbilt University University of Texas Health Sci. Center, Houston Mayo Clinic – Jacksonville, Florida 1:50 p.m. Talk Guoqian Jiang caCDE-QA: A Quality Assurance Platform for Cancer Study Common Data Elements Mayo Clinic – Rochester, Minnesota 2:10 p.m. Talk Hong Yu EMR Adverse Drug Event Detection for Pharmacovigilance University of Massachusetts Medical School 2:30 p.m. Talk Guergana Savova Cancer Deep Phenotyping Extraction from Electronic Medical Records Boston Children’s Hospital University of Pittsburgh 3:05 p.m. Break Session Chair: Brian Haas Advanced Omics 1 PI Name(s) Title Institute 3:25 p.m. Talk Gabor Marth, Aaron Quinlan Monitoring Tumor Subclonal Heterogeneity Over Time and Space University of Utah 3:45 p.m. Talk Dinler Antunes Structure-Based Selection of Tumor-Antigens for T-Cell Based Immunotherapy Rice University 4:05 p.m. Talk Xinshu Grace Xiao Informatics Tools for Single-Nucleotide Analysis of Cancer RNA-Seq University of California, Los Angeles 4:25 p.m. Talk Brian Haas Trinity: Transcriptome Assembly for Genetic and Functional Analysis of Cancer Broad Institute 4:45 p.m. Keynote Ben Raphael Algorithms for Inferring Evolution and Migration of Tumors Brown University
5:30 p.m. Dinner and poster session 7:30 p.m. Close of Day 1 Day 2, Thursday, June 1 8:00 a.m. Breakfast 8:25 a.m. Welcome Josh Stuart & TBD Session Chair: Andrey Fedorov Imaging 2 PI Name(s) Title Institute 8:30 a.m. Talk Andrey Fedorov Quantitative Image Informatics for Cancer Research (QIICR) Brigham and Women’s Hospital Harvard Medical School 8:50 a.m. Talk John Flavin, Steve Moore Integrative Imaging Informatics for Cancer Research Washington University in St. Louis 9:10 a.m. Talk Anant Madabhushi, Anne Martel Pathology Image Informatics Platform for Visualization, Analysis and Management Case Western Reserve University; Ohio State University; University of Toronto 9:30 a.m. Talk Kun Huang Informatics Links between Histological Features and Genetics in Cancer Ohio State University 9:50 a.m. Talk Jayashree Kalpathy-Cramer Informatics Tools for Optimized Imaging Biomarkers for Cancer Research & Discovery Massachusetts General Hospital 10:10 a.m. Talk Joel Saltz Tools to Analyze Morphology and Spatially Mapped Molecular Data Stony Brook University 10:30 a.m. Break Break Break Break Session Chair: Jing Zhu Resources 2 PI Name(s) Title Institute 10:50 a.m. Talk Jill Mesirov The Integrative Genomics Viewer (IGV): Visualization Supporting Cancer Research University of California, San Diego 11:10 a.m. Talk Timothy Griffin, Pratik Jagtap A Galaxy-Based Multi-Omic Informatics Hub for Cancer Researchers University of Minnesota 11:30 a.m. Talk Josh Stuart, Kyle Ellrott BMEG: Biomedical Evidence Graph University of California, Santa Cruz; Oregon Health Sciences University 11:50 a.m. Talk Trey Ideker, Dexter Pratt NDEx – the Network Data Exchange, A Network Commons for Biologists University of California, San Diego 12:10 p.m. Talk Jing Zhu, David Haussler UCSC Xena – Cloud Based Resource for Data Hosting, Visualization and Analysis University of California, Santa Cruz 12:30 p.m. Lunch Session Chair: Alexander Krasnitz Advanced Omics 2 PI Name(s) Title Institute 1:30 p.m. Talk Han Liang The Cancer Proteome Atlas, TCPA: An Integrated Bioinformatics Resource for Functional Cancer Proteomic Data University of Texas MD Anderson Cancer Center 1:50 p.m. Talk Dongjun Chung Algorithms for Literature-Guided Multi-Platform Identification of Cancer Subtypes Medical University of South Carolina 2:10 p.m. Talk Alexander Krasnitz Computational Framework for Single-Cell Genomics of Tumors Cold Spring Harbor Laboratory 2:30 p.m. Talk Jingshan Huang OmniSearch: A Semantic Search Tool for Discovering MicroRNAs‘ Critical Roles in Human Cancer University of South Alabama 2:50 p.m. Break Session Chair: Hiroyuki Yoshida Imaging 3 PI Name(s) Title Institute 3:10 p.m. Talk Srinivas Chakra Chennubhotla, Daryl (Brion) Sarachan Informatics Tools for Tumor Heterogeneity in Multiplexed Fluorescence Images University of Pittsburgh 3:30 p.m. Talk Trinity Urban Next Steps for LesionTracker: Integration with a Clinical Trials Workflow Informatics System Harvard Medical School 3:50 p.m. Talk David Andrew Gutman Advanced Development of an Open-source Platform for Web-based Integrative Digital Image Analysis in Cancer Emory University 4:10 p.m. Group Discussion Collaborative Opportunitites N/A 4:40 p.m. Closing Remarks Juli Klemm and Josh Stuart 5-8 p.m. Beach BBQ (Optional) Natural Bridges Beach