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Tags: Synthetic lethality

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  1. NCI / FNL Workshop on RAS Synthetic Lethality

    25 Feb 2014 | | Contributor(s):: James Hartley

    "Synthetic lethality" is a term of classical genetics that refers to a combination of defective genes that is deadly together (synthetically, i.e., when both genes A and B are inactivated) but not when one or the other (A or B) is inactive. It is known that animal models of cancer can be...