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Quantitative Volume and Density Response Assessment: Sarcoma and HCC as a Model

By Lawrence H Schwartz1, Binsheng Zhao1

1. Columbia University Medical Center, New York

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Abstract

A critical barrier to the development of new cancer therapies is the lack of evidence validating the imaging methods used for patient response assessment. Our project evaluates the ability of improved image analysis techniques, e.g., tumor volume and necrosis fraction, to assess response in cancers such as HCC and Sarcoma in which RECIST is known to correlate poorly with clinical outcome.

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Researchers should cite this work as follows:

  • Lawrence H Schwartz; Binsheng Zhao (2014), "Quantitative Volume and Density Response Assessment: Sarcoma and HCC as a Model," https://ncihub.cancer.gov/resources/289.

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