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Profile

  • Organization
    Frederick National Laboratory for Cancer Research

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    (not set)

  • Employment Status
    National Laboratory

  • Telephone
    301-846-5060

  • Reason
    (not set)

  • Address
    city:Frederick
    postal:21702
    region:MD
    country:US

  • Biography
    Yvonne A. Evrard, PhD is the Operations and Program Manager for the NCI Patient-Derived Models Repository (PDMR, pdmr.cancer.gov). She provides scientific oversight for model development, characterization, and preclinical modeling efforts for the PDMR. The PDMR is focused on obtaining clinical specimens from non-hematologic cancers that are underrepresented in the PDX community including rare cancers. Dr. Evrard oversees multiple funding opportunities for acquisition of patient tumor material for model development as well as deposition of patient-derived models from outside researchers into the PDMR. All models are associated with the medical history from consented patients including current and prior therapies and patient response. Using these data as well as NextGen sequencing, Dr. Evrard helps implement preclinical studies for new combination therapies and novel therapeutics. Dr. Evrard oversees daily operations of the PDMR and coordinates the efforts of the interdisciplinary team that are needed for this effort. She has a research background in developmental biology, generation of transgenic mouse models, chromatin biology, and molecular biology.