Hi all, following up on our successful meeting at Pathology Informatics last May, we thought it would be interesting and educational for our WG members to organize a series of webinars on WSI-related topics.  We kick-off this effort with a talk by Philips’ Prarthana Shrestha on WSI Image Quality.  See Title and Abstract below as well as login information. 

Please attend and bring any questions and comments so we can have a nice discussion following the presentation. 

You may also be interested to know that Aldo Badano from the FDA/CDRH Division of Imaging, Diagnostics, and Software Reliability will be presenting at Pathology Visions on “Interoperability and Component Testing in Whole-Slide Imaging Systems: Lessons from the regulatory history of accessories in radiology.”

On behalf of the organizing committee,

Marios Gavrielides, Ph.D.


Title:      Quantifying image quality of Whole Slide Imaging (WSI) scanners

Abstract:  The quality of an image produced by the Whole Slide Imaging (WSI) scanners is of critical importance for using the image in clinical diagnosis. Therefore, it is very important to monitor and ensure the quality of images. Since subjective image quality assessments by pathologists are very time-consuming, expensive and difficult to reproduce, we propose a method for objective assessment based on clinically relevant and perceptual image parameters: sharpness, contrast, brightness, uniform illumination and color separation; derived from a survey of pathologists. We developed techniques to quantify the parameters based on content-dependent absolute pixel performance and to manipulate the parameters in a predefined range resulting in images with content-independent relative quality measures. The method does not require a prior reference model. A subjective assessment of the image quality is performed involving 69 pathologists and 372 images (including 12 optimal quality images and their distorted versions per parameter at 6 different levels). The results of the subjective assessment support the validity of the proposed objective image quality assessment method to model the readers' perception of image quality. The subjective assessment also provides thresholds for determining the acceptable level of objective quality per parameter. The images for both the subjective and objective quality assessment are based on the HercepTest slides scanned by the Philips Ultra Fast Scanners, developed at Philips Digital Pathology Solutions. However, the method is applicable also to other types of slide stains and scanners. The method was successfully applied to evaluate WSI scanner reproducibility.


WSI WG webinar by Philips: Quantifying image quality of WSI scanners

Monday, October 16, 2017

10:00 am  |  Eastern Daylight Time (New York, GMT-04:00)  |  1 hr


Meeting number: 748 117 909


Meeting password: 1234




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Files/presentations of the one day workshop at Barco, headquarters, Kortrijk, Belgium, 25th of April 2016

Industrial workshop on digital pathology: “Image quality in digital pathology from slide acquisition to visualization”

Direct links to the publications:













  • 8H45: Welcome and introduction
  • 9H00: Introduction session: the opinion of pathologists
    • Pr Illyas – University of Nottingham – Queen Medical Centre - UK
  • 9h30: Session: on Image Quality
    • 30’: Basics of display image quality  - Johanna Rousson – Barco – Belgium
    • 30’: Image Quality in Digital Pathology - Ana Jiménez– VISILAB - UCLM – Spain
  • 10h30: Coffee break & demos
  • 11H00: Session: QA through the chain – part 1
    • 30’: Scanner
      • How Whole Slide Images (WSI) are the first steps for a good Quality Workflow? – Quynh-Nhu Trinh-Xuan Kramer - Hamamatsu – France
    • 60’: Display
      • 30’: Color calibration and ICC profiles - Gert Van Hoey - Barco – Belgium
      • 30’: What you see is what you get (WYSIWYG): Is that enough?- Mark Clymer – Datacolor – via webex
  • 12h30: Lunch
  • 14H00: Session: QA through the chain – part 2
    • 60’: QA Image analysis:
      • 30’: Image Quality from an Image Cytometry Point-of-View – Radu Rogojanu – TissueGnostics – Austria
      • 30’: Image Quality from an open source platform – Raphaël Marée – Cytomine – Belgium
    • 30’: Solving current issues
      • Implementation of DICOM 145 supplement on whole slides images - David de Mena García  - Hospital de Jerez de la Frontera, Cádiz - Spain
  • 15H30: Coffee break & demos
  • 16H00: Session: on clinical and perceptual evaluation studies
    • 60’: Display
      • 30’: Influence of study design in psycho-visual image quality evaluation: Why a specific clinical task? - Ljiljana Platiša – Gent University - IPI/Telin department – Belgium
      • 30’: Influence of display parameters on digital pathology systems - Cédric Marchessoux – Barco – Belgium
  • 17H00: end

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